Since there is no specific antidote, treatment is primarily supportive. The risk of ECG changes associated with torsade de pointes should be considered. With accidental overdosage, hypertension rather than hypotension occurred in a two-year old child. The extrapyramidal reactions would be manifested by muscular weakness or rigidity and a generalized or localized tremor as demonstrated by the akinetic or agitans types respectively. The patient would appear comatose with respiratory depression and hypotension which could be severe enough to produce a shock-like state. In general, the symptoms of overdosage by haloperidol would be an exaggeration of known pharmacologic effects and adverse reactions, the most prominent of which would be: severe extrapyramidal reactions, hypotension or sedation.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. The maximum dose is 20mg/day.Ĭontrolled trials to establish the safety and effectiveness of intramuscular administration in children have not been conducted. Depending on the response of the patient, subsequent doses may be given, administered as often as every hour, although 4 to 8 hour intervals may be satisfactory. Parenteral medication, administered intramuscularly in doses of 2 to 5 mg, is utilized for prompt control of the acutelyagitated schizophrenic patient with moderately severe to very severe symptoms. The optimal response in such patients is usually obtained with more gradual dosage adjustments and at lower dosage levels. Debilitated or geriatric patients, as well as those with a history of adverse reactions to antipsychotic drugs, may require less Haldol (Haloperidol). To determine the initial dosage, consideration should be given to the patient's age, severity of illness, previous response to other antipsychotic drugs, and any concomitant medication or disease state. Dosage adjustments, either upward or downward, should be carried out as rapidly as practicable to achieve optimum therapeutic control. As with all drugs used to treat schizophrenia, dosage should be individualized according to the needs and response of each patient. There is considerable variation from patient to patient in the amount of medication required for treatment. Hypersensitivity to this drug - hypersensitivity reactions have included anaphylactic reaction and angioedema.Severe toxic central nervous system depression or comatose states from any cause.Haldol (Haloperidol) tablets are contraindicated in patients with: This medication is also prescribed for the control of tics and vocal utterances of Tourette's Disorder. Haldol (Haloperidol) is indicated for use in the treatment of schizophrenia.
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